From: joedees@bellsouth.net
Date: Thu Jul 04 2002 - 21:09:18 MDT
                            What is Mind?
The brain, although being the most complex structure 
existing on Earth - and perhaps in the Universe - is a 
well-defined object: it is a material entity located inside 
the skull, which may be visualized, touched and 
handled. It is composed of chemical substances, 
enzymes and hormones which may be measured and 
analyzed. Its architecture is characterized by neuronal 
cells, pathways and synapses. Its functioning depends 
on neurons, which consume oxygen, exchanging 
chemical substance through their membranes, and 
maintaining states of electrical polarization interrupted 
by brief periods of depolarization. 
But... what about the mind? 
It is amazing to verify that even after several centuries 
of philosophical ponderations, hard dedication to brain 
research and remarkable advances in the field of 
neuroscience, the concept of mind still remains 
obscure, controversial and impossible to define within 
the limits of our language. 
One strongly held view is that the mind is an entity 
distinct from the brain; this speculation has its 
historical roots: the early theories, termed dualistic 
hypotheses of the brain function, which stated that the 
material brain can be viewed mechanistically but that 
mind is some entity with different and undefined 
physical character. In such theories the mind was seen 
as synonymous with the soul, forming an integral part 
of the prevailing religious culture. For example, René 
Descartes (1596-1650) the french philosopher, 
perpetuated Plato's (428-348 B.C.) mind-body dualism 
philosophically separating the mind and the body (1). 
He stimulated the debate "How does the non material 
mind influence the brain and vice versa ?" His ideas 
permeated philosophical and scientific views right up 
to the present day, changing the way in which 
mainstream research approached the problem of self. 
Since the mind and brain were now usually viewed as 
isolated entities, research into these areas was 
inherently separate; biochemists concerned themselves 
with objective somatic mechanisms, psychologists 
wrestled with the subjective properties of the mind; 
philosophers and theologians carried with them the 
spirit and soul. 
Mindis a definition which tries to rescue the essence of 
man. The essence of a person arises from the existence 
of mental functions which permit him or her to think 
and to perceive, to love and to hate, to learn and to 
remember, to solve problems, to communicate through 
speech and writing, to create and to destroy 
civilizations. These expressions are closely related with 
brain functioning. Therefore, without the brain, the 
mind cannot exist, without the behavioral 
manifestation, the mind cannot be expressed. 
Spirit and soul seem to be religious and metaphysical 
interpretations of the mind. Neuroscience has 
understood the brain and the mind as a result of 
experimental investigation. Acceptance or rejection of 
the existence of the spirit and soul depends on faith 
and religious conviction, which cannot be proved or 
disproved by experimental methods. It seems to be 
more coherent to think that beliefs are dependent on 
physiological activity of the brain and of our cultural 
environment. We cannot have religious concepts if we 
do not have a functioning brain (e.g., as when the brain 
activity is blocked by coma or deep anesthesia) and we 
cannot believe in things which we do not learn, hear, or 
experience. It is not impossible to think that some 
people can "learn" to believe in the existence of God, 
life after death and supernatural forces because the 
brain is provided with emotional centers in order to 
satisfy psychological needs. I frequently ask myself: "Is 
there any brain region involved with mystic-religious 
experience? Could either lesions or absence of those 
regions abolish religious beliefs? Or, on the contray, 
could "electrical storms" (hyperstimulation of neuronal 
circuits) provoked by psychotic or epileptic seizure be 
acting on specific brain circuitry that processes a 
possible religious feeling?" 
Scientists are generally reluctant to combine 
experimental work with philosophy and usually reject 
consideration of possible theological implications of 
their studies. However, a few studies in this field have 
begun to appear. Saver & Rabin (2) found that clues to 
the neural substrates of religious experience, near-
death experiences and the intake of hallucinogens may 
be deduced from limbic epilepsy (the limbic system is 
described as the emotional system of the brain). 
Ramachandran (3) reported that patients with temporal 
seizures (the temporal lobe is involved with many 
complex functions including emotion and memory) 
sometimes experience God and religious ectasy during 
seizures and are intensely religious. Assal & 
Bindschaedier (4) reported a case of religious delusion 
in a 39-year-old woman who had suffered a head injury 
with right temporal concussion 13 years before. 
Few neuroscientists, such as the Nobel Prize recipient 
Sir John Eccles, asserted that the mind is distinct from 
the body, but most of them now believe that all aspects 
of mind, which are often equated with consciousness, 
are likely to be explained in a more materialistic way as 
the behavior of neuronal cells. In the opinion of the 
famous neurophysiologist José Maria Delgado (5) "it is 
preferable to consider the mind as a functional entity 
devoid of metaphysical or religious implications per se 
and related only to the existence of a brain and to the 
reception of sensory inputs". 
If the brain has explained the mind, how to explain 
mental events as being caused by the activity of large 
sets of neural cells? Neuroscientists, timidly, have 
begun to combat the idea that this question is either 
purely philosophical or elusive to study experimentally 
and have been approaching the problem scientifically. 
They have begun to gain some understanding of 
possible brain mechanisms that may underlie the most 
complex process in human behavior and experience, 
such as the phenomena of consciousness, attention 
and thought. 
Certainly, one of the most remarkable examples to 
illustrate the relationship between the brain and the 
consciousness are the findings which state that there 
seems to be "two brains" in each head (6), that is, each 
hemisphere (each half of the brain) is anatomically a 
mirror image of each other, since most structures are 
present in both sides and they communicate by 
massive bands of fiber systems. Functionally, however, 
each hemisphere has its own areas of mental 
specialization, a phenomenon we call "brain 
lateralization". For example, the left hemisphere is 
involved in highly verbal and rational functions, while 
the right hemisphere is related to artistic and spatio-
visual functions. The interconnecting fibers play an 
important role in coordinating the activities of the 
hemispheres; their lesion may cause the individual to 
behave as if the two hemisphere were responsible for 
two separate consciousnesses, as firstly noted by R. 
Sperry (who was awarded the Nobel for that). In other 
words, if the "bridge" between the two hemispheres is 
destroyed one half of our brain cannot know what the 
other is doing. 
Another significant finding in neurosciences is the 
correlation of mental events such as learning with 
chemicals and structural changes of the nerve cells (7). 
Currently, we know that in our brain new neuronal 
branches growth in response to environmental and 
cultural diversity, that is, to training and experience. 
Each neuron seems to contribute to many behaviors 
and mental activities. Modern techniques are now 
beginning to reveal how the brain accomplishes the 
remarkable feat of learning. Networks of artificial 
neurons on conventional computers are helping to 
explain the ability of the brain to process and to retain 
information. Also, modern cognitive sciences, which 
use a vast array of new techniques, are being able to 
study objectively many components of mental process, 
such as attention, awareness, visual cognition, 
language, mental imagery, etc., and are being 
correlated with neural activity by means of 
computerized functional imaging and are now open to 
scientific investigation. 
Finally, we realize not only the brightness and 
fascination exerted on us by human mental functions, 
which is responsible for the creation and evolution of 
our society, but also by the darkness and despair of 
mental dysfunctions, which destroy and affect the 
internal and external environments of the human being. 
Also in this field, the impressive advances in 
neuroscience and genetics are revealing the anatomic, 
biochemical and hereditary bases of schizophrenia, 
mania, affective and mood disorders, anxiety, 
intellectual deficits, memory disturbances and many 
other (8, 9). 
In conclusion, more and more we are realizing what so 
many influential philosophers and theologians of past 
centuries could not understand: that the brain is 
complex enough to account for the mysteries of 
learning, memory, emotion, creativity, consciousness, 
mystical-religious experience and madness. If we agree 
to think about the mind as it were a set of mental 
functions rather than a spirit, soul or immaterial 
substance, it will becomes easier to get on with the 
necessary empirical studies and thus substantial 
progress could be made not only in the search for the 
nature of man as a cognitive individual, but also in the 
alleviation of mental ills and in a better understanding 
of cultural and religious beliefs, which, along so many 
centuries have brought great pleasures - and afflictions 
- to Humankind. 
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